Guy Twa

Bio

Guy Twa is a Ph.D. candidate in Genetics, Genomics, and Bioinformatics with seven years of research experience in genetics and genomics. Experienced in processing and analyzing bulk and single-cell genomic sequence data from various model systems using statistics and machine learning approaches. Proficient in R, Python, and Bash programming to create and implement bioinformatics workflows for large datasets in high-performance computing cluster environments. I am passionate about understanding how genomic regulatory systems integrate and adapt to information from their environment.

Education

University of Alabama at Birmingham | Birmingham, AL

Ph.D. in Biomedical Sciences August 2021 - Present

University of Alabama at Birmingham | Birmingham, AL

M.S. in Biomedical Sciences | May 2021

University of Alabama at Birmingham | Birmingham, AL

B.S. in Genetics and Genomic Sciences | May 2020

Publications

  1. Wallen ZD, Demirkan A, Twa G, Cohen G, Dean MN, Standaert DG, Sampson T, Payami H. Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms. Nat Commun 13, 6958 (2022). https://doi.org/10.1038/s41467-022-34667-x

  2. Scull CE, Twa G, Zhang Y, Yang NJ, Hunter RN III, Augelli-Szafran CE, Schneider DA. Small Molecule RBI2 Disrupts Ribosome Biogenesis through Pre-rRNA Depletion. Cancers. 2023; 15(13):3303. https://doi.org/10.3390/cancers15133303

Preprints

  1. Twa G, Phillips III R, Robinson N, Day J. Accurate sample deconvolution of pooled snRNA-seq using sex-dependent gene expression patterns. bioRxiv. 2024 Dec 03; doi: https://doi.org/10.1101/2024.11.29.626066

Guy Twa

Bio

Guy Twa is a Ph.D. candidate in Genetics, Genomics, and Bioinformatics with seven years of research experience in genetics and genomics. Experienced in processing and analyzing bulk and single-cell genomic sequence data from various model systems using statistics and machine learning approaches. Proficient in R, Python, and Bash programming to create and implement bioinformatics workflows for large datasets in high-performance computing cluster environments. I am passionate about understanding how genomic regulatory systems integrate and adapt to information from their environment.

Education

University of Alabama at Birmingham | Birmingham, AL

Ph.D. in Biomedical Sciences August 2021 - Present

University of Alabama at Birmingham | Birmingham, AL

M.S. in Biomedical Sciences | May 2021

University of Alabama at Birmingham | Birmingham, AL

B.S. in Genetics and Genomic Sciences | May 2020

Publications

  1. Wallen ZD, Demirkan A, Twa G, Cohen G, Dean MN, Standaert DG, Sampson T, Payami H. Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms. Nat Commun 13, 6958 (2022). https://doi.org/10.1038/s41467-022-34667-x

  2. Scull CE, Twa G, Zhang Y, Yang NJ, Hunter RN III, Augelli-Szafran CE, Schneider DA. Small Molecule RBI2 Disrupts Ribosome Biogenesis through Pre-rRNA Depletion. Cancers. 2023; 15(13):3303. https://doi.org/10.3390/cancers15133303

Preprints

  1. Twa G, Phillips III R, Robinson N, Day J. Accurate sample deconvolution of pooled snRNA-seq using sex-dependent gene expression patterns. bioRxiv. 2024 Dec 03; doi: https://doi.org/10.1101/2024.11.29.626066